Publications
Bioengineering Methods for Analysis of Cells In Vitro
G. H. Underhill, P. Galie, C.S. Chen, S. N. Bhatia
Annu. Rev. Cell Dev. Biol. (2012)
Manuscript (PDF)
A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis
N. E. Reticker-Flynn, D. F. B. Malta, M. M. Winslow, J. M. Lamar, M. J. Xu, G. H. Underhill, R. O. Hynes, T. E. Jacks, S. N. Bhatia
Nature Communications (2012)
Manuscript + Supporting information (PDF)
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
C. P. El-Haibi, G. W. Bell, J. Zhang, A. Y. Collmann, D. Wood, C. M. Scherber, E. Csizmadia, O. Mariani, C. Zhu, A. Campagne, M. Toner, S. N. Bhatia, D. Irimia, A. Vincent-Salomon, A. E. Karnoub
PNAS (2012)
Manuscript + Supporting information (PDF)
Cancer Vulnerabilities Unveiled by Genomic Loss
D. Nijhawan, T. I. Zack, Y. Ren, M. R. Strickland, R. Lamothe, S. E. Schumacher, A. Tsherniak, H. C. Besche, J. Rosenbluh, S. Shehata, G. S. Cowley, B. A. Weir, A. L. Goldberg, J. P. Mesirov, D. E. Root, S. N. Bhatia, R. Beroukhim, W. C. Hahn
Cell (2012)
Manuscript + Supporting information (PDF)
The challenges posed by cancer heterogeneity
S.N. Bhatia, J.V. Frangioni, R. M. Hoffman, A. J. Iafrate, K. Polyak
Nature Biotechnology (2012)
Manuscript (PDF)
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
J. S. Miller, K. R. Stevens, M. T. Yang, B. M. Baker, D.-H. T. Nguyen, D. M. Cohen, E. Toro, A. A. Chen, P. A. Galie, X. Yu, R. Chaturvedi, S. N. Bhatia, C. S. Chen
Nature Materials (2012)
Manuscript (PDF)
A Biophysical Indicator of Vaso-occlusive Risk in Sickle Cell Disease
D. K. Wood, A. Soriano, L. Mahadevan, J. M. Higgins S. N. Bhatia
Science Translational Medicine (2012)
Manuscript (PDF)
Modeling hepatitis C virus infection using human induced pluripotent stem cells
R. E. Schwartz, K. Trehan, L. Andrus, T. P. Sheahan, A. Ploss, S. A. Duncan, C. M. Rice, S. N. Bhatia
PNAS (2012)
Manuscript (PDF)
What is the greatest regulatory challenge in the translation of biomaterials to the clinic?
G. D. Prestwich, S. Bhatia, C. K. Breuer, S. L. M. Dahl, C. Mason, R. McFarland, D. J. McQuillan, J. Sackner-Bernstein, J. Schox, W. E. Tente, A. Trounson
Science Translational Medicine (2012)
Manuscript (PDF)
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
Andrus, Linda; Marukian, Svetlana; Jones, Christopher T; Catanese, Maria Teresa; Sheahan, Timothy P; Schoggins, John W; Barry, Walter T; Dustin, Lynn B; Trehan, Kartik; Ploss, Alexander; Sangeeta N Bhatia; Rice, Charles M
Hepatology (2011)
Manuscript (PDF)
Bioresponsive mesoporous silica nanoparticles for triggered drug release
Singh, Neetu; Karambelkar, Amrita; Gu, Luo; Kevin Y Lin; Miller, Jordan S; Chen, Christopher S; Sailor, Michael J; Sangeeta N Bhatia
Journal of the American Chemical Society (2011)
Manuscript (PDF)
DNA-templated assembly of droplet-derived PEG microtissues
Li, Cheri Y; Wood, David K; Hsu, Caroline M; Sangeeta N Bhatia
Lab on a Chip (2011)
Manuscript (PDF)
Humanized mice with ectopic artificial liver tissues
A.A. Chen, D. K. Thomas, L.L. Ong, L. Luvena, R.E. Schwartz, T.R. Golub, S.N. Bhatia.
PNAS (2011)
Manuscript (PDF)
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
Cheung, Hiu Wing; Cowley, Glenn S; Weir, Barbara A; Boehm, Jesse S; Rusin, Scott; Scott, Justine A; East, Alexandra; Ali, Levi D; Lizotte, Patrick H; Wong, Terence C; Jiang, Guozhi; Hsiao, Jessica; Mermel, Craig H; Getz, Gad; Barretina, Jordi; Gopal, Shuba; Tamayo, Pablo; Gould, Joshua; Tsherniak, Aviad; Stransky, Nicolas; Luo, Biao; Ren, Yin; Drapkin, Ronny; Sangeeta N Bhatia; Mesirov, Jill P; Garraway, Levi A; Meyerson, Matthew; Lander, Eric S; Root, David E; Hahn, William C
PNAS (2011)
Manuscript (PDF)
Nanoparticles that communicate in vivo to amplify tumour targeting
von Maltzahn, Geoffrey; Park, Ji-Ho; Kevin Y Lin; Singh, Neetu; Schwöppe, Christian; Mesters, Rolf; Berdel, Wolfgang E; Ruoslahti, Erkki; Sailor, Michael J; Sangeeta N Bhatia
Nature Materials (2011)
Manuscript (PDF)
In-silico patterning of vascular mesenchymal cells in three dimensions
Tal Danino; Volfson, Dmitri; Sangeeta N Bhatia; Tsimring, Lev; Jeff Hasty
PLoS One (2011)
Manuscript (PDF)
Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells
Goldberg, Michael S; Xing, Deyin; Ren, Yin; Orsulic, Sandra; Sangeeta N Bhatia; Sharp, Phillip A
PNAS (2011)
Manuscript (PDF)
Gold nanorod photothermal therapy in a genetically engineered mouse model of soft tissue sarcoma
Kevin Y Lin†; Alexander F Bagley†; Alexia Y. Zhang; Daniel L. Karl; Sam S. Yoon; Sangeeta N Bhatia
Nano LIFE (2011)
Manuscript (PDF)
Multiplexed, high-throughput analysis of 3D microtissue suspensions
Chen, Alice A; Underhill, Gregory H; Sangeeta N Bhatia
Integrative Biology (2010)
Manuscript (PDF)
Ligand-clustered "patchy" nanoparticles for modulated cellular uptake and in vivo tumor targeting
Poon, Zhiyong; Chen, Shujun; Engler, Amanda C; Lee, Hyung-il; Atas, Evrim; von Maltzahn, Geoffrey; Sangeeta N Bhatia; Hammond, Paula T
Angewandte Chemie (2010)
Manuscript (PDF)