Publications
Depolarization signatures map gold nanorods within biological tissue
N. Lippok, Villiger, M., Albanese, A., Meijer, E. F. J., Chung, K., Padera, T. P., Bhatia, S. N., and Bouma, B. E.
Nature Photonics (2017)
Manuscript (PDF), Supporting information (PDF)
Future cancer research priorities in the USA: a Lancet Oncology Commission
E. M. Jaffee, Van Dang, C., Agus, D. B., Alexander, B. M., Anderson, K. C., Ashworth, A., Barker, A. D., Bastani, R., Bhatia, S., Bluestone, J. A., Brawley, O., Butte, A. J., Coit, D. G., Davidson, N. E., Davis, M., DePinho, R. A., Diasio, R. B., Draetta, G., A Frazier, L., Futreal, A., Gambhir, S. S., Ganz, P. A., Garraway, L., Gerson, S., Gupta, S., Heath, J., Hoffman, R. I., Hudis, C., Hughes-Halbert, C., Ibrahim, R., Jadvar, H., Kavanagh, B., Kittles, R., Le, Q. - T., Lippman, S. M., Mankoff, D., Mardis, E. R., Mayer, D. K., McMasters, K., Meropol, N. J., Mitchell, B., Naredi, P., Ornish, D., Pawlik, T. M., Peppercorn, J., Pomper, M. G., Raghavan, D., Ritchie, C., Schwarz, S. W., Sullivan, R., Wahl, R., Wolchok, J. D., Wong, S. L., and Yung, A.
The Lancet Oncology (2017)
Manuscript (PDF)
Activity-Based Diagnostics: An emerging paradigm for disease detection and monitoring
A.P. Soleimany and S.N. Bhatia
Trends in Molecular Medicine (2020)
Manuscript (PDF)
Urinary detection of lung cancer in mice via noninvasive pulmonary protease profiling
J. D. Kirkpatrick, A. D. Warren, A. P. Soleimany, P. M. K. Westcott, J. C. Voog, C. Martin-Alonso, H. E. Fleming, T. Tammela, T. Jacks, and S. N. Bhatia
Science Translational Medicine (2020)
Manuscript (PDF), Supporting information (PDF)
Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes
E. Michailidis, K. Vercauteren, L. Mancio-Silva, L. Andrus, C. Jahan, I. Ricardo-Lax, C. Zou, M. Kabbani, P. Park, C. Quirk, C. Pyrgaki, B. Razooky, L. Verhoye, I. Zoluthkin, W. Lu, S.J. Forbes, L. Chiriboga, N.D. Theise, R.W. Herzog, H. Suemizu, W.M. Schneider, A. Shlomai, P. Meuleman, S.N. Bhatia, C.M. Rice, Y.P. de Jong.
Proc Natl Acad Sci USA 117, 1678–1688 (2020)
Manuscript (PDF), Supplementary Information (PDF)
Targeting Liver Stage Malaria With Metformin
Vera, I. M., Grilo Ruivo, M. T., Lemos Rocha, L. F., Marques, S., Bhatia, S. N., Mota, M. M. & Mancio-Silva, L.
JCI Insight 4, (2019)
Manuscript (PDF)
Theranostic Layer-by-Layer Nanoparticles for Simultaneous Tumor Detection and Gene Silencing.
N. Boehnke, S. Correa, L. Hao, W. Wang, J. P. Straehla, S. N. Bhatia, P. T. Hammond.
Angew Chem Int Ed Engl. 59, 2776–2783 (2020).
Manuscript (PDF), Supporting information (PDF)
Non-viral delivery of CRISPR/Cas9 complex using CRISPR-GPS nanocomplexes
P. K. Jain, J. H. Lo, S. Rananaware, M. Downing, A. Panda, M. Tai, S. Raghavan, H. E. Fleming, S. N. Bhatia.
Nanoscale. 11, 21317–21323 (2019).
Manuscript (PDF), Supporting information (PDF)
Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer
M.-E. Gilles, L. Hao, K. Brown, J. Lim, S. N. Bhatia, F. J. Slack
Oncotarget. 10, 5349–5358 (2019).
Manuscript (PDF), Supporting information (PDF)
Renal clearable catalytic gold nanoclusters for in vivo disease monitoring
C. N. Loynachan †, A. P. Soleimany †, J. S. Dudani, Y. Lin, A. Najer, A. Bekdemir, Q. Chen, S. N. Bhatia, and M. M. Stevens
Nat. Nanotechnol. 14, 883–890 (2019).
Manuscript (PDF), Supporting information (PDF)
Antimalarial Activity of Primaquine Operates via a Two-Step Biochemical Relay
Camarda, G., Jirawatcharadech, P., Priestley, R. S., Saif, A., March, S., Wong, M. H. L., Leung, S., Miller, A. B., Baker, D. A., Alano, P., Paine, M. J. I., Bhatia, S. N., O’Neill, P. M., Ward, S. A. & Biagini, G. A.
Nat. Commun. 10, 3226 (2019)
Manuscript (PDF), Supporting Information (PDF)
Synthetic and living micropropellers for convection-enhanced nanoparticle transport
Schuerle, S., Soleimany, A. P., Yeh, T., Anand, G. M., Häberli, M., Fleming, H. E., Mirkhani, N., Qiu, F., Hauert, S., Wang, X., Nelson, B. J. & Bhatia, S. N.
Sci. Adv. 5, eaav4803 (2019).
Manuscript (PDF), Supporting information (PDF)
Steroid Hormone Function Controls Non-competitive Plasmodium Development in Anopheles
Werling, K., Shaw, W. R., Itoe, M. A., Westervelt, K. A., Marcenac, P., Paton, D. G., Peng, D., Singh, N., Smidler, A. L., South, A., Deik, A. A., Mancio-Silva, L., Demas, A. R., March, S., Calvo, E., Bhatia, S. N., Clish, C. B. & Catteruccia, F.
Cell. 177, 315-325.e14 (2019).
Manuscript (PDF), Supporting information (PDF)
Improving drug discovery by nucleic acid delivery in engineered human microlivers
L. Mancio-Silva, H. E. Fleming, A. B. Miller, S. Milstein, A. Liebow, P. Haslett, L. Sepp-Lorenzino, and S. N. Bhatia.
Cell Metabolism (2019)
Manuscript (PDF), Supporting information (PDF)
Acidification of tumor at stromal boundaries drives transcriptome alterations associated with aggressive phenotypes
Rohani, N., Hao, L., Alexis, M. S., Joughin, B. A., Krismer, K., Moufarrej, M. N., Soltis, A. R., Lauffenburger, D. A., Yaffe, M. B., Burge, C. B., Bhatia, S. N. & Gertler, F. B.
Cancer Res. 79, 1952–1966 (2019).
Manuscript (PDF), Supporting information (PDF)
Uncovering and Mitigating Algorithmic Bias through Learned Latent Structure
A. Amini†, Soleimany, A. †, Schwarting, W., Bhatia, S. N., and Rus, D.
AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society, 2019
Manuscript (PDF)
Estrogen Activation of G protein-coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes
S. Chaturantabut, Shwartz, A., Evason, K. J., Cox, A. G., Labella, K., Schepers, A. G., Yang, S., Aravena, M., Houvras, iv, Y., Mancio-Silva, L., Romano, S., Gorelick, D. A., Cohen, D. E., Zon, L. I., Bhatia, S. N., North, T. E., and Goessling, W.
Gastroenterology, 2019
Manuscript (PDF)
Protease activity sensors noninvasively classify bacterial infections and antibiotic responses
C. Buss †, J.S. Dudani †, R. Akana, H.E. Fleming, and S.N. Bhatia
EBioMedicine (2018)
Manuscript (PDF), Supporting information (PDF)