Publications
Oxygen Is a Factor Determining In Vitro Tissue Assembly: Effects on Attachment and Spreading of Hepatocytes
Avi Rotem, Mehmet Toner, Sangeeta Bhatia, Brent D. Foy, and Ronald G. Tompkins, and Martin L. Yarmush
Biotechnology and Bioengineering (1994)
Manuscript (PDF)
Degradable hydrogels derived from peg-diacrylamide for hepatic tissue engineering
Stevens, K.R., Miller, J.S., Blakely, B.L., Chen, C.S., and Bhatia, S.N.
J Biomed Mater Res A (2015)
Manuscript (PDF)
Quantifying co-cultured cell phenotypes in high-throughput using pixel-based classification
Logan, D.J., Shan, J., Bhatia, S.N., and Carpenter, A.E.
Methods (2015)
Manuscript (PDF), Supporting information (PDF)
Microscale culture of human liver cells for drug development
S. Khetani and S. Bhatia.
Nature Biotechnology (2008)
Manuscript (PDF), Supporting information (PDF)
Identification of small molecules for human hepatocyte expansion and iPS differentiation
J. Shan, R.E. Schwartz, N.T. Ross, D.J. Logan, D. Thomas, S.A Duncan, T.E. North, W. Goessling, A.E. Carpenter, and S.N. Bhatia
Nature Chemical Biology (2013)
Manuscript (PDF), Supporting information (PDF)
Nanoparticles that communicate in vivo to amplify tumour targeting
G. von Maltzahn, J.H. Park, K. Y. Lin, N. Singh, C. Schwöppe, R. Mesters, W. E. Berdel, E. Ruoslahti, M. J. Sailor, and S. N. Bhatia
Nature Materials (2011)
Manuscript (PDF), Supplementary information (PDF)
Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4
Y. Ren, H. W. Cheung, G. von Maltzhan, A. Agrawal, G.S. Cowley, B. A. Weir, J. S. Boehm, P. Tamayo, A. M. Karst, J. F. Liu, M. S. Hirsch, J. P. Mesirov, R. Drapkin, D. E. Root, J. Lo, V. Fogal, E. Ruoslahti, W. C. Hahn,* S. N. Bhatia*
Science Translational Medicine (2012)
Manuscript (PDF), Supporting information (PDF)
Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease
G. A. Kwong, G. von Maltzahn, G. Murugappan, O. Abudayyeh, S. Mo, I. A. Papayannopoulos, D.Y. Sverdlov, S. B. Liu, A.D. Warren, Y. Popov, D. Schuppan, and S.N. Bhatia
Nature Biotechnology (2013)
Manuscript (PDF), Supporting information (PDF)
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
A. Ploss, S. R. Khetani, C. T. Jones, A. J. Syder, K. Trehan, V. A. Gaysinskaya, K. Mu, K. Ritola, C. M. Rice, and S. N. Bhatia
Proceedings of the National Academy of Sciences (2010)
Manuscript (PDF), Supporting information (PDF)
Mapping functional humoral correlates of protection against malaria challenge following RTS,S/AS01 vaccination
Suscovich, T. J., Fallon, J. K., Das, J., Demas, A. R., Crain, J., Linde, C. H., Michell, A., Natarajan, H., Arevalo, C., Broge, T., Linnekin, T., Kulkarni, V., Lu, R., Slein, M. D., Luedemann, C., Marquette, M., March, S., Weiner, J., Gregory, S., Coccia, M., Flores-Garcia, Y., Zavala, F., Ackerman, M. E., Bergmann-Leitner, E., Hendriks, J., Sadoff, J., Dutta, S., Bhatia, S. N., Lauffenburger, D. A., Jongert, E., Wille-Reece, U. & Alter, G.
Sci. Transl. Med. 12, (2020).
Manuscript (PDF), Supporting Information (PDF)
Controlled apoptosis of stromal cells to engineer human microlivers
A.X. Chen, A. Chhabra, H.-H. G.Song, H.E. Fleming, C.S. Chen, and S.N. Bhatia
Advanced Functional Materials (2020)
Manuscript (PDF), Supporting Information (PDF)
Nanoparticle delivery of immunostimulatory oligonucleotides enhances response to checkpoint inhibitor therapeutics
C. G. Buss and S. N. Bhatia
Proceedings of the National Academy of Sciences (2020)
Manuscript (PDF), Supporting Information (PDF)
Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines
N. K. Mehta, Pradhan, R. V., Soleimany, A. P., Moynihan, K. D., Rothschilds, A. M., Momin, N., Rakhra, K., Mata-Fink, J., Bhatia, S. N., K. Wittrup, D., and Irvine, D. J.
Nature Biomedical Engineering. (2020)
Manuscript (PDF), Supporting Information (PDF)
Cancer Cell–Derived Matrisome Proteins Promote Metastasis in Pancreatic Ductal Adenocarcinoma
C. Tian, hlund, D. Ö., Rickelt, S., m, Tö, Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., and Hynes, R. O.
Cancer Research, vol. 80, no. 7, pp. 1461 - 1474 (2020)
Manuscript (PDF)
Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers
S. Ng, March, S., Galstian, A., Gural, N., Stevens, K. R., Mota, M. M., and Bhatia, S. N., Scientific Reports, vol. 7, no. 45424, 2017.
Manuscript (PDF), Supporting information (PDF)
Ultrasensitive tumour-penetrating nanosensors of protease activity
E. J. Kwon†, Dudani, J. S. †, and Bhatia, S. N.
Nature Biomedical Engineering (2017)
Manuscript (PDF), Supporting information (PDF)
Porous Silicon Nanoparticle Delivery of Tandem Peptide Anti-Infectives for the Treatment of Pseudomonas aeruginosa Lung Infections
E. J. Kwon, Skalak, M., Bertucci, A., Braun, G., Ricci, F., Ruoslahti, E., Sailor, M. J., and Bhatia, S. N.
Advanced Materials, vol. 29, no. 35, pp. 1-9, 2017.
Manuscript (PDF), Supporting information (PDF)
In situ expansion of engineered human liver tissue in a mouse model of chronic liver disease
K. R. Stevens, M.A. Scull, V. Ramanan, C.L. Fortin, R.R. Chaturvedi, K.A. Knouse, J.W. Xiao, C. Fung, T. Mirabella, A.X. Chen, M.G. McCue, M.T. Yang, H.E. Fleming, K. Chung, Y.P. de Jong, C.S. Chen, C.M. Rice, and S.N. Bhatia.
Science Translational Medicine (2017)
Manuscript (PDF), Supporting information (PDF)